BDBM50203236 CHEMBL3906933

SMILES Cn1c(cc2c(N)nc(N)nc12)-c1cccc(Cl)c1

InChI Key InChIKey=OKCPDTBJQUNNKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50203236   

TargetDihydrofolate reductase(Homo sapiens (Human))
Turing Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203236(CHEMBL3906933)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human DHFR expressed in Escherichia coli preincubated for 15 mins followed by addition of DHF as substrate and NADPH measur...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Turing Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50203236(CHEMBL3906933)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Toxoplasma gondii TS-DHFR expressed in Escherichia coli BL21 preincubated for 15 mins followed by addition of DHF as substrate and NADP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed