BDBM50203985 (E)-1-(2,4-dihydroxyphenyl)-3-(2,4-dihydroxyphenyl)-2-propen-1-one (18)::2,2',4,4'-tetrahydroxychalcone::2,4,2',4'-tetrahydroxychalcone::CHEMBL394855
SMILES Oc1ccc(\C=C\C(=O)c2ccc(O)cc2O)c(O)c1
InChI Key InChIKey=ZWTDXYUDJYDHJR-QHHAFSJGSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50203985
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute of Material Medica, Chinese Academy of Sciences
Shanghai Institute of Material Medica, Chinese Academy of Sciences
Affinity DataIC50: 620nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of Rattus norvegicus (rat) lens aldose reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of tyrosinase in mouse B16 cells assessed as reduction in melanin synthesis after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of tyrosinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mushroom tyrosinase assessed as reduction in diphenolase activity using L-DOPA substrate pre-incubated for 20 mins at 30 degCMore data for this Ligand-Target Pair