BDBM50205722 (2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(methoxyamino)-9H-purin-9-yl)-3,4-dihydroxy-N-methyltetrahydrofuran-2-carboxamide::2-[(4-fluorophenyl)ethynyl]-N6-methoxy-5'-N-methylcarboxamidoadenosine::CHEMBL427077

SMILES CNC(=O)[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(NOC)nc(nc12)C#Cc1ccc(F)cc1

InChI Key InChIKey=ONKUERGTTKQFGY-KSVNGYGVSA-N

Data  7 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50205722   

TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity to human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataKi:  3.00E+3nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataKi:  1.87E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataKi:  1.87E+4nMAssay Description:Displacement of [3H]NECA from human recombinant adenosine A2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50205722((2S,3S,4R,5R)-5-(2-((4-fluorophenyl)ethynyl)-6-(me...)
Affinity DataEC50:  210nMAssay Description:Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as nonradiaoactive DELFIA Eu-GTP binding treated for 15 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed