BDBM50206432 4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid::CHEMBL222509

SMILES OC(=O)c1ccc(Nc2nc(Cl)nc(Cl)n2)cc1-c1c2ccc(O)cc2oc2cc(=O)ccc12

InChI Key InChIKey=NJQHZBRWPXRTIW-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50206432   

TargetDeoxyribonuclease-1(Homo sapiens (Human))
University Of Nis

Curated by ChEMBL
LigandPNGBDBM50206432(4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of DNase 1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease gamma(Homo sapiens (Human))
University Of Nis

Curated by ChEMBL
LigandPNGBDBM50206432(4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of DNase gamma (unknown origin) transfected in HeLa S3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRmtA(Emericella nidulans)
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50206432(4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of Aspergillus nidulans recombinant GST-RmtA expressed in BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease gamma(Homo sapiens (Human))
University Of Nis

Curated by ChEMBL
LigandPNGBDBM50206432(4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of DNase gamma-mediated HMGB1 release expressed in human staurosporine-induced HeLaS3 cells treated 1 hr before staurosporine challenge me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1 [11-371](Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50206432(4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...)
Affinity DataIC50:  1.89E+4nMAssay Description:Inhibition of human recombinant GST-PRMT1 expressed in BL21 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeoxyribonuclease gamma(Homo sapiens (Human))
University Of Nis

Curated by ChEMBL
LigandPNGBDBM50206432(4-(4,6-dichloro-1,3,5-triazin-2-ylamino)-2-(6-hydr...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of human recombinant DNase gamma expressed in Rosetta DE3 cells assessed as increase in acidsoluble DNA after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed