BDBM50206758 CHEMBL3898537
SMILES CC(C)Oc1ccc(Br)c(CC2CCN(CCc3cc4OCCOc4cc3Cl)CC2)c1
InChI Key InChIKey=SBUGQNDLQATQQL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50206758
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sumitomo Dainippon Pharma
Curated by ChEMBL
Sumitomo Dainippon Pharma
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of human SERT expressed in CHO cell membranes assessed as reduction in [3H]serotonin uptake preincubated for 10 mins followed by [3H]serot...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma
Curated by ChEMBL
Sumitomo Dainippon Pharma
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A receptor expressed in CHOK1 cells after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes assessed as reduction in formation of 1'-hydroxy-bufuralol from bufuralol preincubated with enzyme fol...More data for this Ligand-Target Pair