BDBM50207089 D-1-Methyltryptophan::D-1MT::Indoximod
SMILES Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12
InChI Key InChIKey=ZADWXFSZEAPBJS-SNVBAGLBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 50207089
Affinity DataKi: 1.90E+4nMAssay Description:Binding affinity to human IDO1 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataKi: 3.40E+4nMAssay Description:Binding affinity to IDO1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 3.50E+4nMAssay Description:Binding affinity to IDO1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 3.30E+6nMAssay Description:Inhibition of recombinant human IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynurenine formation using ...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+5nMAssay Description:Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+8nMAssay Description:Inhibition of human IDO1More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+6nMAssay Description:Inhibition of IDO1 in human HeLa cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of IDO1 in human HeLa assessed as reduction in kynurenine productionMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Transcriptional activation in CV-1 cells expressing human glucocorticoid receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 9.56E+4nMAssay Description:Inhibition of recombinant human His-tagged IDO1 expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of kynurenine production using L...More data for this Ligand-Target Pair
Affinity DataIC50: 2.63E+5nMAssay Description:Inhibition of recombinant human C-terminal His6-tagged IDO2 (14-420 residues) expressed in Escherichia coli BL21(DE3) assessed as reduction in L-kynu...More data for this Ligand-Target Pair
Affinity DataIC50: 1.49E+5nMAssay Description:Inhibition of recombinant human IDO2 expressed in human U87MG cells assessed as reduction in kynurenine formation using L-tryptophan as substrate aft...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+6nMAssay Description:Inhibition of IDO1 in human HT-29 assessed as reduction in kynurenine productionMore data for this Ligand-Target Pair