BDBM50209220 CHEMBL3884187

SMILES FC(F)(F)c1c(OC2CC(C2)c2ccccc2)ccn2c(CC3CC3)nnc12

InChI Key InChIKey=RRXBINRLCLVQAK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50209220   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50209220(CHEMBL3884187)
Affinity DataEC50:  0.5nMAssay Description:Positive allosteric modulation of human mGlu2 receptor expressed in HEK293 cells coexpressing rat glutamate transporter assessed as inhibition of for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed