BDBM50210630 CHEMBL3929796

SMILES Cl.OC(=O)C(Cc1ccc2cc(OCCCN3CCNCC3)ccc2c1)NS(=O)(=O)c1ccccc1

InChI Key InChIKey=XCMTVJLJLLVGGK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50210630   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50:  1.32E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of collagen-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50:  1.01E+3nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of U46619-induced platelet aggregation preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50:  530nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of thrombin-induced platelet aggregation preincubated ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50:  80nMAssay Description:Displacement of fibrinogen from human platelet GP2b/GP3a receptor after 2 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50210630(CHEMBL3929796)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at GP2b/GP3a receptor in human platelet rich plasma assessed as inhibition of ADP-induced platelet aggregation preincubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed