BDBM50216333 CHEBI:67357::DOLASTATIN-10::Dolastatin 10::Dolostatin 10

SMILES [H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1

InChI Key InChIKey=OFDNQWIFNXBECV-VFSYNPLYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216333   

TargetSimilar to alpha-tubulin isoform 1(Bos taurus)
Upr 9023 Cnrs

Curated by ChEMBL
LigandPNGBDBM50216333(CHEBI:67357 | DOLASTATIN-10 | Dolastatin 10 | Dolo...)
Affinity DataIC50:  2.20E+3nMAssay Description:In vitro inhibition of tubulin polymerization measured as turbidity formed by centrifugationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
Laboratoire Des M£Canismes Mol£Culaires Des Communications Cellulaires (Cnrs Upr 9023)

Curated by ChEMBL
LigandPNGBDBM50216333(CHEBI:67357 | DOLASTATIN-10 | Dolastatin 10 | Dolo...)
Affinity DataIC50:  2.20E+3nMAssay Description:Compound was tested in vitro for inhibition of tubulin polymerization.More data for this Ligand-Target Pair