BDBM50216915 2-(2-adamantylamino)-5-methyl-5-(trifluoromethyl)-1,3-oxazol-4(5H)-one::CHEMBL237798

SMILES CC1(OC(NC2C3CC4CC(C3)CC2C4)=NC1=O)C(F)(F)F

InChI Key InChIKey=ZNKDCFOGYMXTMF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216915   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216915(2-(2-adamantylamino)-5-methyl-5-(trifluoromethyl)-...)
Affinity DataKi:  7nMAssay Description:Binding affinity to human 11beta-HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216915(2-(2-adamantylamino)-5-methyl-5-(trifluoromethyl)-...)
Affinity DataIC50:  59nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed