BDBM50216918 8-benzyl-2-[(S)-1-(2-trifluoromethyl-phenyl)-ethylamino]-1-oxa-3,8-diaza-spiro[4.5]dec-2-en-4-one::CHEMBL392489

SMILES C[C@H](NC1=NC(=O)C2(CCN(Cc3ccccc3)CC2)O1)c1ccccc1C(F)(F)F

InChI Key InChIKey=RLGHAIWROQIAPF-INIZCTEOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216918   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216918(8-benzyl-2-[(S)-1-(2-trifluoromethyl-phenyl)-ethyl...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human 11beta-HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216918(8-benzyl-2-[(S)-1-(2-trifluoromethyl-phenyl)-ethyl...)
Affinity DataIC50:  29nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed