BDBM50216922 5-isopropyl-5-methyl-2-[(S)-1-(2-trifluoromethyl-phenyl)-ethylamino]-oxazol-4-one::CHEMBL237107

SMILES CC(C)C1(C)OC(N[C@@H](C)c2ccccc2C(F)(F)F)=NC1=O

InChI Key InChIKey=PMQDVLRNHJDGJS-MYHCZTBNSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216922   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216922(5-isopropyl-5-methyl-2-[(S)-1-(2-trifluoromethyl-p...)
Affinity DataKi:  46nMAssay Description:Binding affinity to human 11beta-HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216922(5-isopropyl-5-methyl-2-[(S)-1-(2-trifluoromethyl-p...)
Affinity DataIC50:  12nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed