BDBM50216928 2-(1-adamantylamino)-1,8-dioxa-3-azaspiro[4.5]dec-2-en-4-one::CHEMBL235017

SMILES O=C1N=C(NC23CC4CC(CC(C4)C2)C3)OC11CCOCC1

InChI Key InChIKey=XRXMHWIGTLVZGF-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50216928   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216928(2-(1-adamantylamino)-1,8-dioxa-3-azaspiro[4.5]dec-...)
Affinity DataKi:  43nMAssay Description:Binding affinity to human 11beta-HSD1 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216928(2-(1-adamantylamino)-1,8-dioxa-3-azaspiro[4.5]dec-...)
Affinity DataIC50:  273nMAssay Description:Inhibition of 11beta-HSD1 in human adipocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed