BDBM50221085 (3R,4S)-1-(6-(3-fluorophenyl)pyrimidin-4-yl)-4-(2,4,5-trifluorophenyl)pyrrolidin-3-amine::CHEMBL237343

SMILES N[C@H]1CN(C[C@@H]1c1cc(F)c(F)cc1F)c1cc(ncn1)-c1cccc(F)c1

InChI Key InChIKey=XDQKNXBLASGZHN-KDOFPFPSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221085   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221085((3R,4S)-1-(6-(3-fluorophenyl)pyrimidin-4-yl)-4-(2,...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of human recombinant DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221085((3R,4S)-1-(6-(3-fluorophenyl)pyrimidin-4-yl)-4-(2,...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human recombinant DPP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221085((3R,4S)-1-(6-(3-fluorophenyl)pyrimidin-4-yl)-4-(2,...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human recombinant DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221085((3R,4S)-1-(6-(3-fluorophenyl)pyrimidin-4-yl)-4-(2,...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human recombinant DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed