BDBM50221967 (2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)-3-fluoro-pyrrolidin-1-yl)-N,N-dimethyl-4-oxo-butyramide::(2S,3S)-3-amino-2-(4'-fluorobiphenyl-4-yl)-4-((S)-3-fluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxobutanamide::CHEMBL237119

SMILES CN(C)C(=O)[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=YPGNHGMZLLVIHB-UFYCRDLUSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50221967   

TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  6.90E+4nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Matrix Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  24nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50: >100nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  69nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221967((2S,3S)-3-amino-2-(4'-fluoro-biphenyl-4-yl)-4-((S)...)
Affinity DataIC50:  0.0120nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed