BDBM50223675 CHEMBL251369::N-(2-morpholinophenyl)-5-nitrofuran-2-carboxamide::cid_2996093

SMILES [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccccc1N1CCOCC1

InChI Key InChIKey=BIQWNNXDPVEAPZ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223675   

TargetV-type proton ATPase subunit c'(Saccharomyces cerevisiae S288c)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50223675(CHEMBL251369 | N-(2-morpholinophenyl)-5-nitrofuran...)
Affinity DataEC50:  2.53E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1 R03 DA031666-01A1 Project Title: Flow Cytometry HTS of Small Molecules that Regulate V-ATPa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Johnson And Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50223675(CHEMBL251369 | N-(2-morpholinophenyl)-5-nitrofuran...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of ATP-induced autophosphorylation of cFMS tyrosine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetV-type proton ATPase subunit c'(Saccharomyces cerevisiae S288c)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50223675(CHEMBL251369 | N-(2-morpholinophenyl)-5-nitrofuran...)
Affinity DataEC50:  4.18E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1 R03 DA031666-01A1 Project Title: Flow Cytometry HTS of Small Molecules that Regulate V-ATPa...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay