BDBM50223798 CHEMBL391451::N-(5'-deoxy-alpha-D-thymidin-5'-yl)-N'-(3-trifluoromethyl-4-chlorophenyl)urea

SMILES Cc1cn([C@@H]2C[C@H](O)[C@@H](CNC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)O2)c(=O)[nH]c1=O

InChI Key InChIKey=FIFLVFXOJCAQLR-MJBXVCDLSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50223798   

TargetThymidylate kinase(Mycobacterium tuberculosis)
University Of Gent

Curated by ChEMBL
LigandPNGBDBM50223798(CHEMBL391451 | N-(5'-deoxy-alpha-D-thymidin-5'-yl)...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis TMPK expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdTMP kinase(Plasmodium falciparum (isolate 3D7))
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50223798(CHEMBL391451 | N-(5'-deoxy-alpha-D-thymidin-5'-yl)...)
Affinity DataKi:  8.80E+4nMAssay Description:Inhibition of recombinant Plasmodium falciparum TMPK using TMP as substrate by pyruvate kinase and lactate dehydrogenase enzyme coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed