BDBM50224870 (6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocine-8-carboxylic acid [2-(3-bromo-phenyl)-ethyl]-amide::CHEMBL250993

SMILES C[C@H]1C2Cc3ccc(cc3[C@@]1(C)CCN2CC1CC1)C(=O)NCCc1cccc(Br)c1

InChI Key InChIKey=CFCYDKRYHOSVHZ-CGOBKJRRSA-N

Data  3 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50224870   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.0630nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  3.5nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataIC50:  230nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed