BDBM50225078 CHEMBL400739::methyl ((S)-2-(2-(1-(7-aza-bicyclo[2.2.1]heptan-7-yl)-2-methyl-1-oxopropan-2-yl)-5-(3,5-dimethylphenyl)-6H-thieno[2,3-b]pyrrol-4-yl)propylamino)(3-(pyridin-4-yl)pyrrolidin-1-yl)methylenecarbamate

SMILES COC(=O)N=C(NC[C@@H](C)c1c([nH]c2sc(cc12)C(C)(C)C(=O)N1C2CCC1CC2)-c1cc(C)cc(C)c1)N1CCC(C1)c1ccncc1

InChI Key InChIKey=LBNVTKXFWRBTPJ-IEXYTZDRSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225078   

TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225078(CHEMBL400739 | methyl ((S)-2-(2-(1-(7-aza-bicyclo[...)
Affinity DataIC50:  3nMAssay Description:Antagonist activity at GnRH receptor expressed in AP Han Wistar rat primary pitutary cells assessed as inhibition of GnRH stimulated LH release after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225078(CHEMBL400739 | methyl ((S)-2-(2-(1-(7-aza-bicyclo[...)
Affinity DataIC50:  35nMAssay Description:Displacement of [125I]D-Trp from human GnRH receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50225078(CHEMBL400739 | methyl ((S)-2-(2-(1-(7-aza-bicyclo[...)
Affinity DataIC50:  8nMAssay Description:Displacement of [125I]D-Trp from rat GnRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed