BDBM50227996 (6S,7S)-7-hydroxycarbamoyl-6-(4-phenyl-3,4-dihydro-2H-pyridine-1-carbonyl)-5-aza-spiro[2.5]octane-5-carboxylic acid isobutyl ester::CHEMBL403185
SMILES CC(C)COC(=O)N1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCC(C=C1)c1ccccc1)C(=O)NO
InChI Key InChIKey=PEAOAVRAGQRJEO-AKQSQHNNSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50227996
Affinity DataIC50: 451nMAssay Description:Binding affinity to MMP9More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Binding affinity to MMP2More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Incyte
Curated by ChEMBL
Incyte
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of HER2 sheddase in BT474 cells by extracellular domain shedding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Binding affinity to MMP3More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Binding affinity to MMP1More data for this Ligand-Target Pair