BDBM50229634 (S)-tetrahydrofuran-3-yl 4-((4-(4-cyanophenyl)piperidin-1-ylsulfonyl)methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate::CHEMBL253890

SMILES ONC(=O)C1(CS(=O)(=O)N2CCC(CC2)c2ccc(cc2)C#N)CCN(CC1)C(=O)O[C@H]1CCOC1

InChI Key InChIKey=BTZCYRDTCBYYDO-NRFANRHFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50229634   

LigandPNGBDBM50229634((S)-tetrahydrofuran-3-yl 4-((4-(4-cyanophenyl)pipe...)
Affinity DataIC50:  77nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229634((S)-tetrahydrofuran-3-yl 4-((4-(4-cyanophenyl)pipe...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50229634((S)-tetrahydrofuran-3-yl 4-((4-(4-cyanophenyl)pipe...)
Affinity DataIC50:  39nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed