BDBM50229646 (R)-pyrrolidin-2-ylmethyl 4-(hydroxycarbamoyl)-4-((4-o-tolylpiperidin-1-ylsulfonyl)methyl)piperidine-1-carboxylate::CHEMBL253020

SMILES Cc1ccccc1C1CCN(CC1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC[C@H]1CCCN1)C(=O)NO

InChI Key InChIKey=IKHATIJQVUIUCY-OAQYLSRUSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50229646   

LigandPNGBDBM50229646((R)-pyrrolidin-2-ylmethyl 4-(hydroxycarbamoyl)-4-(...)
Affinity DataIC50:  19nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229646((R)-pyrrolidin-2-ylmethyl 4-(hydroxycarbamoyl)-4-(...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50229646((R)-pyrrolidin-2-ylmethyl 4-(hydroxycarbamoyl)-4-(...)
Affinity DataIC50:  30nMAssay Description:Inhibition of HER2 sheddase in human BT474 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Incyte

Curated by ChEMBL
LigandPNGBDBM50229646((R)-pyrrolidin-2-ylmethyl 4-(hydroxycarbamoyl)-4-(...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed