BDBM50230001 4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazol-5-yl)pyridine::4-(4-fluorophenyl)-2-(4-nitrophenyl)-5-(4-pyridyl)-1H-imidazole::4-[5-(4-Fluoro-phenyl)-2-(4-nitro-phenyl)-3H-imidazol-4-yl]-pyridine::CHEMBL17331::PD-169316

SMILES [O-][N+](=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key InChIKey=BGIYKDUASORTBB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50230001   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory activity against 5-lipoxygenase enzyme from RBL-1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against interleukin-1(IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Korea Institute Of Science & Technology (Kist School)

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...)
Affinity DataIC50:  89nMAssay Description:Inhibition of p38 alpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...)
Affinity DataIC50:  89nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50230001(4-(4-(4-fluorophenyl)-2-(4-nitrophenyl)-1H-imidazo...)
Affinity DataIC50:  89nMAssay Description:Inhibition of tyrosinase in mouse B16F10 cells assessed as reduction in melanin synthesis after 2 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed