BDBM50230170 CHEMBL4100979
SMILES Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)c(F)c4)cc3)c12
InChI Key InChIKey=DEMGLABBZSLUOH-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50230170
Affinity DataIC50: 0.130nMAssay Description:Inhibition of EphB4 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Xi'An Jiaotong University
Curated by ChEMBL
Xi'An Jiaotong University
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of VEGFR2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of TIE-2 (unknown origin) after 60 mins by ADP-Glo assayMore data for this Ligand-Target Pair