BDBM50232347 CHEMBL4089840
SMILES O=C(COc1cccc2c1cc[nH]c2=O)c1ccccc1
InChI Key InChIKey=JJWMRRNGWSITSQ-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50232347
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of recombinant human His6-tagged PARP1 autophosphorylation at ADP-ribosyltransferase domain by LC-MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP2 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 5.75E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins fol...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 ADP-ribosyltransferase domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins fol...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 3.09E+3nMAssay Description:Inhibition of recombinant human TNKS1 ADP-ribosyltransferase/sterile alpha motif domain expressed in Escherichia coli BL21(DE3) preincubated for 15 m...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant human TNKS1 ADP-ribosyltransferase/sterile alpha motif domain expressed in Escherichia coli BL21(DE3) preincubated for 15 m...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 1.07E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP2 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP3 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of PARP1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP3(Homo sapiens (Human))
Health & Science University
Curated by ChEMBL
Health & Science University
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full length recombinant human His6-tagged PARP3 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair