BDBM50232529 5-(2-fluorobenzyloxy)quinazoline-2,4-diamine::CHEMBL251427

SMILES Nc1nc(N)c2c(OCc3ccccc3F)cccc2n1

InChI Key InChIKey=SFJOSBAEWKPKPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232529   

TargetDihydrofolate reductase(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50232529(5-(2-fluorobenzyloxy)quinazoline-2,4-diamine | CHE...)
Affinity DataIC50:  0.390nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed