BDBM50233558 (R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylisoxazol-3-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)benzamide::CHEMBL253927

SMILES CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)on1

InChI Key InChIKey=VYOMLNMMWYPDOS-GFCCVEGCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50233558   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50233558((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylisoxaz...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50233558((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylisoxaz...)
Affinity DataIC50:  171nMAssay Description:Inhibition of CXCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50233558((R)-2-hydroxy-N,N-dimethyl-3-(2-(1-(5-methylisoxaz...)
Affinity DataIC50:  12.2nMAssay Description:Inhibition of CXCR2-mediated chemotaxis in Ba/F3 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed