BDBM50233576 (R)-3-(2-(1-(4-bromofuran-2-yl)propylamino)-3,4-dioxocyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL401939

SMILES CC[C@@H](Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(Br)co1

InChI Key InChIKey=UNUGDTFIICVXIP-GFCCVEGCSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50233576   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50233576((R)-3-(2-(1-(4-bromofuran-2-yl)propylamino)-3,4-di...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50233576((R)-3-(2-(1-(4-bromofuran-2-yl)propylamino)-3,4-di...)
Affinity DataIC50:  55nMAssay Description:Inhibition of CXCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50233576((R)-3-(2-(1-(4-bromofuran-2-yl)propylamino)-3,4-di...)
Affinity DataIC50:  917nMAssay Description:Inhibition of CXCR1-mediated chemotaxis in Ba/F3 cells expressing human CXCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50233576((R)-3-(2-(1-(4-bromofuran-2-yl)propylamino)-3,4-di...)
Affinity DataIC50:  2nMAssay Description:Inhibition of CXCR2-mediated chemotaxis in Ba/F3 cells expressing human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed