BDBM50233672 CHEMBL4095478

SMILES NC(=O)[C@@H](NC(=O)[C@H](CC1CCCCC1)NC(=O)c1ccno1)C1CCCCC1

InChI Key InChIKey=CAYJNBJPGBBDAS-WMZOPIPTSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50233672   

TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human PAR2 expressed in CHO cells assessed as induction of intracellular calcium release measured for 300 secs by Fluo-3 AM dye-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  270nMAssay Description:Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  2.00E+3nMAssay Description:Agonist activity at PK1-tagged PAR2 (unknown origin) expressed in HEK293 cells assessed as induction of beta-arrestin recruitment incubated for 90 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50233672(CHEMBL4095478)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human PAR2 expressed in HEK293T cells assessed as induction of Galphaq-stimulated IP1 formation incubated for 2 hrs by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed