BDBM50234060 CHEMBL4066497::US9765018, Example 77

SMILES CCCc1ccccc1Oc1ccc(cc1NC(=O)Nc1ccc(C)cc1)-c1ccc(OC)c(c1)C(O)=O

InChI Key InChIKey=UKSHAFQHHFCSFG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50234060   

TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50234060(CHEMBL4066497 | US9765018, Example 77)
Affinity DataIC50:  2.33E+3nMAssay Description:Human IDO1/HEK293 cells were seeded at 10,000 cells per 50 uL per well with RPMI/phenol red free media contains 10% FBS in a 384-well black wall clea...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM50234060(CHEMBL4066497 | US9765018, Example 77)
Affinity DataIC50:  330nMAssay Description:Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells assessed as inhibition of kynurenine production preincubated with cells followed by IFN-g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed