BDBM50234082 CHEMBL4088624::US9701664, Example 52

SMILES Cc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1NC(=O)c1ccc2nc(OCCCN3CCCCC3)ccc2c1

InChI Key InChIKey=IYYAIKPZMIMDEQ-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234082   

TargetPirin(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234082(CHEMBL4088624 | US9701664, Example 52)
Affinity DataKd:  30nMAssay Description:Binding affinity to recombinant human pirin by surface plasma resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234082(CHEMBL4088624 | US9701664, Example 52)
Affinity DataIC50:  6nMAssay Description:The cell titre blue viability (Promega, USA) assay provides a homogenous, fluorometric method for estimating the number of viable cells. It uses the ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock factor protein 1(Homo sapiens (Human))
Cancer Research Technology

US Patent
LigandPNGBDBM50234082(CHEMBL4088624 | US9701664, Example 52)
Affinity DataIC50:  12nMAssay Description:U2OS cells (5-8×104 cells/mL) or SK-OV-3 cells (5-8×104 cells/mL) were seeded into 96-well plates and incubated at 37° C. for 48 h. Compounds were th...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPirin(Homo sapiens (Human))
The Institute Of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50234082(CHEMBL4088624 | US9701664, Example 52)
Affinity DataKd:  30nMAssay Description:Binding affinity to recombinant human pirin by surface plasma resonance methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed