BDBM50234650 2,3,4-trihydroxybenzophenone::CHEMBL1527::Polyhydroxy benzophenone, 17::hsp90_149::phenyl(2,3,4-trihydroxyphenyl)methanone

SMILES Oc1ccc(C(=O)c2ccccc2)c(O)c1O

InChI Key InChIKey=HTQNYBBTZSBWKL-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50234650   

TargetHeat shock protein HSP 90-beta(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50234650(2,3,4-trihydroxybenzophenone | CHEMBL1527 | Polyhy...)
Affinity DataIC50:  5.00E+4nMAssay Description:FRET Assay 1More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAutoinducer 2-binding periplasmic protein LuxP(Vibrio harveyi)
Georgia State University

Curated by ChEMBL
LigandPNGBDBM50234650(2,3,4-trihydroxybenzophenone | CHEMBL1527 | Polyhy...)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at LuxP receptor in Vibrio harveyi MM32 assessed as inhibition of autoinducer2-mediated quorum sensing after 3 to 4 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
Sun Yat-Sen University

LigandPNGBDBM50234650(2,3,4-trihydroxybenzophenone | CHEMBL1527 | Polyhy...)
Affinity DataIC50:  1.05E+4nMpH: 6.8 T: 2°CAssay Description:In brief, a 10 μL sample was added to an assay mixture containing with 10 μL tyrosinase solution (0.5 mg/mL) and 900 μL phosphate buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed