BDBM50234984 CHEMBL3218837

SMILES CC(C)(C)CNC(=O)C[C@H](NC(=O)C(=O)c1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccncc1)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=LJQBIIJYQRCLSH-NSOVKSMOSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50234984   

TargetProteasome subunit beta type-5(Homo sapiens (Human))
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50234984(CHEMBL3218837)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of 20s immunoproteasome chymotrypsin-like activity in human peripheral blood monocyte using Ac-ANW-AMC as substrate in presence of proteas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50234984(CHEMBL3218837)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of constitutive 20S proteasome beta 5 subunit in human erythrocytes using Ac-WLA-AMC as substrate in presence of PA28alpha by fluorimetry ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50234984(CHEMBL3218837)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of 20S immunoproteasome beta 5i subunit in human peripheral blood monocyte using Ac-ANW-AMC as substrate in presence of PA28alpha by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Hangzhou Xixi Hospital

Curated by ChEMBL
LigandPNGBDBM50234984(CHEMBL3218837)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of 20s immunoproteasome chymotrypsin-like activity in human peripheral blood monocyte using Ac-ANW-AMC as substrate in presence of proteas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed