BDBM50235602 CHEMBL4101440

SMILES CCCC1=N[C@@H](CCCCN2C[C@H](Cc3ccccc3)N(CCCC3CCCC3)C2=S)CN1

InChI Key InChIKey=PGUIOSMKYOTJKP-UIOOFZCWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50235602   

TargetNuclear receptor ROR-alpha(Homo sapiens (Human))
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50235602(CHEMBL4101440)
Affinity DataIC50:  5.80E+3nMAssay Description:Compound was tested for CETP inhibition by a precipitation method to separate lipoproteins after incubation of radiolabeled HDL with LDL and CETP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-beta(Rattus norvegicus)
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50235602(CHEMBL4101440)
Affinity DataIC50:  1.02E+4nMAssay Description:Antagonist activity at rat Gal4-fused DBD RORbeta LBD (Pro-205-end) expressed in TRex-CHOK1 cells after 20 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor ROR-gamma(Mus musculus)
Torrey Pines Institute For Molecular Studies

Curated by ChEMBL
LigandPNGBDBM50235602(CHEMBL4101440)
Affinity DataIC50:  6.40E+3nMAssay Description:Compound was tested for CETP inhibition by a precipitation method to separate lipoproteins after incubation of radiolabeled HDL with LDL and CETP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed