BDBM50236675 CHEMBL4102106

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)N2CCN(C(C2)C(=O)NO)C(=O)C(C)(C)C)c2CCCCc2n1

InChI Key InChIKey=XPKONFJMLMUKJB-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50236675   

TargetMacrophage metalloelastase(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50:  930nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro displacement of [3H]spiperone from the recombinant human dopamine receptor D2 short form expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50: >1.00E+4nMAssay Description:Effect of compound on Metabotropic glutamate receptor 1 expressed in HEK 293 cells was determined by measuring IP production relative to glutamateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 0.2 nM [3H]paroxetine binding to Serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human TACE catalytic domain using Mca-Pro-Leu-Ala-Gln-Ala-Val-Dpa-Arg-Ser-Ser-Ser-Arg-NH2 as substrate after 2 hrs by fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50:  1.30E+3nMAssay Description:Displacement of 0.5 nM [3H]WIN-35248 from Dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 9(Homo sapiens (Human))
Nestl�

Curated by ChEMBL
LigandPNGBDBM50236675(CHEMBL4102106)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ADAM9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed