BDBM50237139 CHEMBL4089863
SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1n[nH]c2ccc(cc12)-c1ccc2ccccc2c1
InChI Key InChIKey=QPNXLQHAJUTVIF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50237139
Affinity DataKi: 147nMAssay Description:In vitro Binding affinity towards 5-hydroxytryptamine 3 receptor was determinedMore data for this Ligand-Target Pair
Affinity DataEC50: 1.77E+3nMAssay Description:Inhibition of wild-type EGFR in human A431 cells assessed as reduction in cell viability after 96 hrs by CellTiterGlo assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of EGF-induced wild-type EGFR phosphorylation in human A431 cells pre-incubated for 1 hr followed by EGF stimulation for 30 mins by Wester...More data for this Ligand-Target Pair
Affinity DataIC50: 8.10nMAssay Description:Inhibition of wild-type human N-terminal GST-tagged EGFR cytoplasmic domain (669 to 1210 end amino acid residues) expressed in baculovirus expression...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Neuronal sodium channel blocking activity by [14C]guanidinium flux assayMore data for this Ligand-Target Pair