BDBM50237153 CHEMBL4098444

SMILES COc1cc(N(C)CCN(C)C)c(NC(=O)C=C)cc1Nc1n[nH]c2cc(ccc12)-c1cn(C)c2ccccc12

InChI Key InChIKey=FOYVLGNZQPYXSS-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237153   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50237153(CHEMBL4098444)
Affinity DataKi:  236nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50237153(CHEMBL4098444)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IVMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tu Dortmund University

Curated by ChEMBL
LigandPNGBDBM50237153(CHEMBL4098444)
Affinity DataEC50:  2.21E+3nMAssay Description:Inhibition of wild-type EGFR in human A431 cells assessed as reduction in cell viability after 96 hrs by CellTiterGlo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed