BDBM50237549 5-(4-hydroxybenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL402183

SMILES [#8]-c1ccc(\[#6]=[#6]-2\[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]-2=O)cc1

InChI Key InChIKey=KSOJQSBHVKAHPC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237549   

TargetMethionine aminopeptidase 1(Homo sapiens (Human))
North Dakota State University

Curated by ChEMBL
LigandPNGBDBM50237549(5-(4-hydroxybenzylidene)pyrimidine-2,4,6(1H,3H,5H)...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human methionine aminopeptidase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
China National Analytical Center (Guangzhou)

Curated by ChEMBL
LigandPNGBDBM50237549(5-(4-hydroxybenzylidene)pyrimidine-2,4,6(1H,3H,5H)...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate assessed as formation of DOPAchrome preincubated for 10 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
China National Analytical Center (Guangzhou)

Curated by ChEMBL
LigandPNGBDBM50237549(5-(4-hydroxybenzylidene)pyrimidine-2,4,6(1H,3H,5H)...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed