BDBM50237739 CHEMBL4091801

SMILES CCN1[C@H]([C@H](c2cccc(Cl)c2F)[C@]2(C(=O)Nc3cc(Cl)ccc23)C11CCCCC1)C(=O)NC12CCC(CC1)(CC2)C(O)=O

InChI Key InChIKey=YJCZPJQGFSSFOL-MNZPCBJKSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50237739   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50237739(CHEMBL4091801)
Affinity DataKi: <1nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50237739(CHEMBL4091801)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of MDM2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Michigan Comprehensive Cancer Center

Curated by ChEMBL
LigandPNGBDBM50237739(CHEMBL4091801)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of FAM-tagged p53-based PMDM6-F peptide binding to human recombinant His-tagged MDM2 (1 to 118 residues) after 30 mins by fluorescence pol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed