BDBM50238199 CHEMBL4099331

SMILES CCc1cc(ccc1\C=C1/SC(=O)NC1=O)-c1ccc(cc1)-n1c(cc(\C=C2/SC(=O)NC2=O)c1-c1cccs1)-c1cccs1

InChI Key InChIKey=DUBOMYBLNFQAAX-SZVCAHDZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50238199   

TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50238199(CHEMBL4099331)
Affinity DataIC50:  391nMAssay Description:Inhibition of recombinant human MCF7 cells derived His-tagged GAC (L123 to S598 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase liver isoform, mitochondrial(Homo sapiens)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50238199(CHEMBL4099331)
Affinity DataIC50:  1.72E+3nMAssay Description:Inhibition of recombinant human His-tagged GAB (P56 to V602 residues) expressed in Escherichia coli C41(DE3)pLysS using glutamine as substrate preinc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutaminase kidney isoform, mitochondrial(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50238199(CHEMBL4099331)
Affinity DataIC50:  54nMAssay Description:Inhibition of recombinant human His-tagged KGA (L123 to L669 residues) expressed in Escherichia coli BL21(DE3)pLysS using glutamine substrate preincu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed