BDBM50238989 CHEMBL4087337

SMILES COc1ccc2O\C(=C/c3ccc(O)c(O)c3)C(=O)c2c1

InChI Key InChIKey=IOJLBZJSULGZLY-CHHVJCJISA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50238989   

TargetAurora kinase A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human AURORA-AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  5.03E+3nMAssay Description:In vitro inhibitory activity against human plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Blk(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  3.05E+3nMAssay Description:Inhibition of human BLKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  510nMAssay Description:Inhibition of human TEKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  8.84E+3nMAssay Description:Inhibition of human CDK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of human ITKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  250nMAssay Description:Inhibition of recombinant GST-tagged DRAK2 (unknown origin) autophosphorylation after 2 hrs by ADP-glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17A(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  5.81E+3nMAssay Description:Inhibition of human DRAK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 2(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  6.34E+3nMAssay Description:Compound was tested for the inhibitory constant for adenosine deaminase (ADA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  1.22E+4nMAssay Description:Inhibition of human DAPK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
East China Normal University

Curated by ChEMBL
LigandPNGBDBM50238989(CHEMBL4087337)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibitory activity against the thymidylate synthase in the Permeabilized L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed