BDBM50239044 CHEMBL4104680

SMILES COC(=O)c1ccc(nc1)-c1cc2cc(Oc3ccc(nc3)S(C)(=O)=O)c(cc2[nH]1)C1CCC(=O)N1C

InChI Key InChIKey=WFBRJBQNYOSYST-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50239044   

TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239044(CHEMBL4104680)
Affinity DataEC50:  8.20nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 2.5 mM glucose by G6PDH coupl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239044(CHEMBL4104680)
Affinity DataEC50:  20nMAssay Description:Activation of glucokinase in primary rat hepatocytes assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50239044(CHEMBL4104680)
Affinity DataEC50:  3.40nMAssay Description:Activation of recombinant human glucokinase assessed as conversion of D-glucose to D-glucose-6-phosphate in presence of 10 mM glucose by G6PDH couple...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHexokinase-4(Rattus norvegicus)
Merck

Curated by ChEMBL
LigandPNGBDBM50239044(CHEMBL4104680)
Affinity DataEC50:  7.80nMAssay Description:Activation of glucokinase in rat INS-1 cells assessed as increase in D-2-deoxyglucose-6-phosphate level in presence of D-2-deoxyglucose by HILIC LC-M...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed