BDBM50239128 CHEMBL4059854::US10266493, Example 2A::US10919858, Example 2A

SMILES CC(C)(Sc1ccncc1-c1ccc(cc1)C#N)C(O)=O

InChI Key InChIKey=IATRELKTSMOMBJ-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50239128   

TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239128(CHEMBL4059854 | US10266493, Example 2A | US1091985...)
Affinity DataIC50: <50nMAssay Description:Inhibition of human URAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239128(CHEMBL4059854 | US10266493, Example 2A | US1091985...)
Affinity DataEC50:  25nMAssay Description:HEK293 human embryonic kidney cells (ATCC #CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% C02 an...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50239128(CHEMBL4059854 | US10266493, Example 2A | US1091985...)
Affinity DataEC50:  26nMAssay Description:HEK293 human embryonic kidney cells (ATCC# CRL-1573) were propagated in EMEM tissue culture medium as described by ATCC in an atmosphere of 5% CO2 an...More data for this Ligand-Target Pair
In DepthDetails US Patent