BDBM50239562 CHEMBL4104179

SMILES CCn1c2NC3=C(C(c4ccc(C)cc4)c2c(=O)[nH]c1=O)C(=O)OC3

InChI Key InChIKey=MUOCQMZJLRQTRD-UHFFFAOYSA-N

Data  2 KI  4 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50239562   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataKi:  370nMAssay Description:Inhibition of BI-BODIPY binding to BRD4 bromodomain 1 (42 to 168 residues)(unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence an...More data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataKi:  690nMAssay Description:Inhibition of BI-BODIPY binding to BRDT bromodomain 1 (29 to 134 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataIC50:  900nMAssay Description:Inhibition of acetylated histone4 (1 to 21 residues) binding to His-tagged BRD4 bromodomain 1 (42 to 168 residues) (unknown origin) expressed in Esch...More data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataKd:  1.60E+3nMAssay Description:Binding affinity to human BRDT bromodomain 1 (21 to 137 residues) expressed in bacterial expression system by q-PCR-based bromoscan assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataKd:  840nMAssay Description:Binding affinity to human BRD4 bromodomain 1 (44 to 168 residues) expressed in bacterial expression system by qPCR-based bromoscan assayMore data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of biotin-labeled (+)-JQ1 binding to His-tagged BRDT bromodomain 1 (29 to 134 residues) (unknown origin) expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 4(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of biotin-labeled (+)-JQ1 binding to His-tagged BRD4 bromodomain 1 (42 to 168 residues) (unknown origin) expressed in Escherichia coli BL2...More data for this Ligand-Target Pair
TargetBromodomain testis-specific protein(Homo sapiens (Human))
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50239562(CHEMBL4104179)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of BI-BODIPY binding to BRDT bromodomain 1 (29 to 134 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) by fluorescence a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed