BDBM50240380 2,6-Bis-(benzylidene)-cyclohexanone::2,6-Bis-[1-phenyl-meth-(E)-ylidene]-cyclohexanone::2,6-dibenzylidenecyclohexanone::CHEMBL274993

SMILES O=C1\C(CCC\C1=C/c1ccccc1)=C\c1ccccc1

InChI Key InChIKey=CTKKGXDAWIAYSA-JSAVKQRWSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50240380   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50240380(2,6-Bis-(benzylidene)-cyclohexanone | 2,6-Bis-[1-p...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50240380(2,6-Bis-(benzylidene)-cyclohexanone | 2,6-Bis-[1-p...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue factor(Homo sapiens (Human))TBA
LigandPNGBDBM50240380(2,6-Bis-(benzylidene)-cyclohexanone | 2,6-Bis-[1-p...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of tissue factor in Homo sapiens (human) THP1-cells using factor 10a chromogenic substrate assessed as inhibition of LPS-iduced procoagula...More data for this Ligand-Target Pair
In DepthDetails Article
TargetTrypanothione reductase(Trypanosoma cruzi)
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50240380(2,6-Bis-(benzylidene)-cyclohexanone | 2,6-Bis-[1-p...)
Affinity DataIC50:  4.58E+4nMAssay Description:Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli BL21(DE3) assessed as reduction of oxidized trypanothione prein...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione reductase, mitochondrial(Homo sapiens (Human))
Universidade Federal De Minas Gerais

Curated by ChEMBL
LigandPNGBDBM50240380(2,6-Bis-(benzylidene)-cyclohexanone | 2,6-Bis-[1-p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant glutathione reductase using glutathione as substrate preincubated for 30 mins by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed