BDBM50240543 CHEMBL4096589

SMILES Fc1ccc(Oc2cc(ncn2)N2CCC(CC2)C(=O)N2Cc3ccccc3C2)c(F)c1

InChI Key InChIKey=AVVMQHQEYKLYQE-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50240543   

TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  340nMAssay Description:Antagonist activity at recombinant human M4 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  478nMAssay Description:Antagonist activity at rat M4 receptor by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  540nMAssay Description:Antagonist activity at recombinant human M1 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  520nMAssay Description:Antagonist activity at recombinant human M2 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  660nMAssay Description:Antagonist activity at recombinant human M3 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M5(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  1.13E+3nMAssay Description:Antagonist activity at recombinant human M5 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  560nMAssay Description:Antagonist activity at rat M4 receptor by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50240543(CHEMBL4096589)
Affinity DataIC50:  324nMAssay Description:Antagonist activity at recombinant human M4 receptor expressed in CHO cells co-expressing Gqi5 by calcium mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed