BDBM50241251 2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfonyl)-amino]-N-[2-(4-sulfamoyl-phenyl)-ethyl]-acetamide::CHEMBL234529::N-(4-Methoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphenyl)ethylcarbamoyl]methyl}aminoacetohydroxamic Acid

SMILES COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)CC(=O)NCCc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=QSOYTCHABFMDFV-UHFFFAOYSA-N

Data  3 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50241251   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  57nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of human recombinant CA1 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp)-OH as substrate after 1 hr by fluorescence assay...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  59nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  44nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  532nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  54nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  90nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50241251(2-[hydroxycarbamoylmethyl-(4-methoxy-benzenesulfon...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed