BDBM50241296 CHEMBL245412::Zerumbone

SMILES C\C1=C/CC(C)(C)\C=C\C(=O)\C(C)=C\CC1

InChI Key InChIKey=GIHNTRQPEMKFKO-SKTNYSRSSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50241296   

TargetCytochrome P450 3A4(Homo sapiens (Human))
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241296(CHEMBL245412 | Zerumbone)
Affinity DataIC50:  2.18E+4nMAssay Description:Inhibition of human CYP3A4 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI2(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50241296(CHEMBL245412 | Zerumbone)
Affinity DataIC50:  910nMAssay Description:Inhibition of Gli2-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetZinc finger protein GLI1(Homo sapiens (Human))
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50241296(CHEMBL245412 | Zerumbone)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of Gli1-mediated transcription expressed in human PANC1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Toyama Medical And Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50241296(CHEMBL245412 | Zerumbone)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human CYP2D6 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed