BDBM50241303 CHEMBL245317::ethyl hydrogen (1-(3-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxyphenylsulfonyl)piperidin-4-yl)methylphosphonate::{1-[3-(1-Methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-propoxy-benzenesulfonyl]-piperidin-4-ylmethyl}-phosphonic acid monoethyl ester

SMILES CCCOc1ccc(cc1-c1nc2c(CCC)nn(C)c2c(=O)[nH]1)S(=O)(=O)N1CCC(CP(O)(=O)OCC)CC1

InChI Key InChIKey=WUUHQGRDQLQCMN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50241303   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50241303(CHEMBL245317 | ethyl hydrogen (1-(3-(1-methyl-7-ox...)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of phosphodiesterase 5 of rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50241303(CHEMBL245317 | ethyl hydrogen (1-(3-(1-methyl-7-ox...)
Affinity DataIC50:  0.170nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50241303(CHEMBL245317 | ethyl hydrogen (1-(3-(1-methyl-7-ox...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of phosphodiesterase 3 from rabbit plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bos taurus)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50241303(CHEMBL245317 | ethyl hydrogen (1-(3-(1-methyl-7-ox...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of phosphodiesterase 6 from bovine retinaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50241303(CHEMBL245317 | ethyl hydrogen (1-(3-(1-methyl-7-ox...)
Affinity DataIC50:  156nMAssay Description:Inhibition of phosphodiesterase 1 from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed