BDBM50241517 CHEMBL4072551

SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N[C@H]1CN2CCC1CC2)c1ccc(cc1)C#N

InChI Key InChIKey=NGEPOLPMLVNHHR-QFIPXVFZSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50241517   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241517(CHEMBL4072551)
Affinity DataIC50:  1.19E+4nMAssay Description:Inhibition of N-terminal truncated human LSD1 (151 to 852 residues) expressed in Escherichia coli after 30 mins using histone H3(1-21)K4(Me1) biotin ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50241517(CHEMBL4072551)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity to LSD1 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed